BDBM50150830 4-[(N-Cyclohexyl-piperazine-1-carboximidoyl)-amino]-N-[2-(2,4-dichloro-phenyl)-ethyl]-benzamide::CHEMBL184275
SMILES Clc1ccc(CCNC(=O)c2ccc(NC(=NC3CCCCC3)N3CCNCC3)cc2)c(Cl)c1
InChI Key InChIKey=YEXGHTGVNJDCFJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50150830
Affinity DataKi: 18nMAssay Description:Inhibition of [125I]-NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Binding affinity for human melanocortin 1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 650nMAssay Description:Binding affinity for human melanocortin 4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMAssay Description:Binding affinity for human melanocortin 3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 1.90E+3nMAssay Description:Agonistic activity for human Melanocortin 4 receptor as stimulated cAMP releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 460nMAssay Description:Inhibition of [125I]NDP-MSH binding to human Melanocortin 5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair