BDBM50150951 CHEMBL3774793

SMILES CN(c1ccc(OCC(=O)NO)cc1)c1ncnc2ccccc12

InChI Key InChIKey=WKPDRDKNRMYFAG-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150951   

TargetHistone deacetylase 1(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50150951(CHEMBL3774793)
Affinity DataIC50:  242nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50150951(CHEMBL3774793)
Affinity DataEC50:  49nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50150951(CHEMBL3774793)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50150951(CHEMBL3774793)
Affinity DataIC50:  14nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed