BDBM50151869 4-(3-(ethyl(3-(propylsulfinyl)propyl)amino)-2-hydroxypropoxy)benzonitrile::4-(3-{Ethyl-[3-(propane-1-sulfinyl)-propyl]-amino}-2-hydroxy-propoxy)-benzonitrile::Almokalant::CHEMBL362103

SMILES CCCS(=O)CCCN(CC)CC(O)COc1ccc(cc1)C#N

InChI Key InChIKey=ZMHOBBKJBYLXFR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50151869   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50151869(4-(3-(ethyl(3-(propylsulfinyl)propyl)amino)-2-hydr...)
Affinity DataIC50:  250nMAssay Description:Inhibitory concentration against IKr potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50151869(4-(3-(ethyl(3-(propylsulfinyl)propyl)amino)-2-hydr...)
Affinity DataIC50:  5.58E+4nMAssay Description:Tested in vitro for dopamine(DA) neuronal uptake inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50151869(4-(3-(ethyl(3-(propylsulfinyl)propyl)amino)-2-hydr...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human ERG potassium channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed