BDBM50152453 8-(2-Ethoxy-ethoxy)-quinolin-2-ylamine::CHEMBL185065

SMILES CCOCCOc1cccc2ccc(N)nc12

InChI Key InChIKey=PVKHCFVJUHKBPZ-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152453   

TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50152453(8-(2-Ethoxy-ethoxy)-quinolin-2-ylamine | CHEMBL185...)
Affinity DataKi:  1.25E+6nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil cytosol factor 1(Homo sapiens)
University Of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50152453(8-(2-Ethoxy-ethoxy)-quinolin-2-ylamine | CHEMBL185...)
Affinity DataKd:  9.87E+5nMAssay Description:Binding affinity to immobilized recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50152453(8-(2-Ethoxy-ethoxy)-quinolin-2-ylamine | CHEMBL185...)
Affinity DataIC50: >2.00E+3nMAssay Description:Concentration required to inhibit binding of [125I]-MCH radioligand to human melanin-concentrating hormone receptor 1 in IMR-32 I3.4.2 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed