BDBM50152522 2-methyl-2-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate::CHEMBL426611::[(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 2-methyl-2-phenyl-propyl ester

SMILES CCCC[C@H](NC(=O)OCC(C)(C)c1ccccc1)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=NTPPZLBAUWCCNL-KNQAVFIVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50152522   

TargetPro-cathepsin H(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152522(2-methyl-2-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of 50 uM L-Arg-beta-naphthalamide binding to human cathepsin H in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152522(2-methyl-2-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of 5 uM Cbz-Phe-Arg-AMC human cathepsin L in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50152522(2-methyl-2-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  64.6nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152522(2-methyl-2-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin B in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50152522(2-methyl-2-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152522(2-methyl-2-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phen...)
Affinity DataIC50:  270nMAssay Description:Inhibition of 10 uM Cbz-Val-Val-Arg-AMC binding to human cathepsin S in fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed