BDBM50152748 (S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carbonyl)-amino]-acetylamino}-3,3-dimethyl-butyryl)-octahydro-cyclopenta[c]pyrrole-1-carboxylic acid [1-((R)-sec-butylaminooxalyl)-butyl]-amide::CHEMBL184715

SMILES CCCC(NC(=O)[C@@H]1C2CCCC2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnccn1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)N[C@H](C)CC

InChI Key InChIKey=QUYMXKYHCFJIIB-SANRFLFRSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50152748   

TargetGenome polyprotein(Hepatitis C virus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50152748((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
Affinity DataKi:  80nMAssay Description:Inhibition of HCV NS3 protease in the pNA based inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50152748((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
Affinity DataKi:  1.30E+4nMAssay Description:Binding affinity towards human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50152748((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50152748((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50152748((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50152748((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50152748((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
Affinity DataKi:  1.07E+5nMAssay Description:Binding affinity towards human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed