BDBM50153595 CHEMBL3775930

SMILES CCn1c(CCC2CCCCC2)nnc1CCC(=O)Nc1ccc(C)cc1C

InChI Key InChIKey=JSSSSJQKWYAZCL-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153595   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153595(CHEMBL3775930)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Mus musculus)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153595(CHEMBL3775930)
Affinity DataEC50:  600nMAssay Description:Inhibition of mouse RORgamma ligand binding domain (Isoleucine 251 to Lysine 516) expressed in CHOK1 cells incubated for 2 days by Gal4 luciferase re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153595(CHEMBL3775930)
Affinity DataEC50:  900nMAssay Description:Inhibition of human RORgamma ligand binding domain (Serine 253 to Lysine 518 residues) expressed in CHOK1 cells incubated for 2 days by Gal4 lucifera...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed