BDBM50154088 7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol::7-bromo-2-(4-hydroxyphenyl)benzo[d]oxazol-5-ol::CHEMBL188528

SMILES Oc1ccc(cc1)-c1nc2cc(O)cc(Br)c2o1

InChI Key InChIKey=BAAILVWEAXFTSF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50154088   

TargetEstrogen receptor beta(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  2nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  155nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(RAT)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  132nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity to ERbeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154088(7-Bromo-2-(4-hydroxy-phenyl)-benzooxazol-5-ol | 7-...)
Affinity DataIC50:  132nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed