BDBM50155446 1,3,7-Trihydroxy xanthone (3)::1,3,7-Trihydroxy-xanthen-9-one::1,3,7-trihydroxy-9H-xanthen-9-one::CHEMBL361025

SMILES Oc1ccc2oc3cc(O)cc(O)c3c(=O)c2c1

InChI Key InChIKey=JJUNZBRHHGLJQW-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50155446   

TargetUrease(Canavalia ensiformis (Jack bean) (Horse bean))
University of Peshawar

LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  1.38E+5nMpH: 6.8 T: 2°CAssay Description:Reaction mixtures comprising 25 μL of enzyme (jack bean urease) solution and 55 μL of buffer containing 100 mM urea were incubated with 5 &...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Unne

Curated by ChEMBL
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  8.00E+3nMAssay Description:Concentration required to inhibit monoamine oxidase activity by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  5.32E+4nMAssay Description:Inhibition of wild type H1N1 swine influenza virus neuraminidase using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  1.47E+4nMAssay Description:Inhibition of baker's yeast alpha-glucosidase using PNP as substrate preincubated for 30 mins followed by sucrose addition and measured after 1 mins ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  1.02E+5nMAssay Description:Inhibition of Influenza A virus H9N2 neuraminidase using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of Influenza A virus H1N1 neuraminidase using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMaltase-glucoamylase(Homo sapiens (Human))TBA
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  3.18E+4nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) using PNPG as substrate preincubated for 15 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as release of p-nitrophenol using pNPG as substrate preincubated for 15 mins follow...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNeuraminidase(Influenza A virus)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50155446(1,3,7-Trihydroxy xanthone (3) | 1,3,7-Trihydroxy-x...)
Affinity DataIC50:  3.72E+4nMAssay Description:Inhibition of oseltamivir-resistant H1N1 swine influenza virus neuraminidase H274Y mutant using 4-MU-NANA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed