BDBM50155579 CHEMBL3546846

SMILES N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccccc2)cc1

InChI Key InChIKey=FFYGOYSNGFPHEN-LSDHHAIUSA-N

Data  4 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50155579   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human LSD1 using H3K4Me1 peptide as substrate incubated for 60 min by peroxidase-coupled methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of recombinant human MAO-B using benzylamine as substrateMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataKi:  6.10E+4nMAssay Description:Inhibition of human LSD2 using H3K4Me2 peptide as substrate incubated for 60 min by peroxidase-coupled methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataIC50:  31nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetREST corepressor 1 [4-485](Homo sapiens (Human))
European Institute Of Oncology

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50155579(CHEMBL3546846)
Affinity DataIC50:  5.83E+4nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed