BDBM50155778 1-[4-((S)-3,10-Dibromo-8-chloro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)-piperidin-1-yl]-2-(1-oxy-pyridin-4-yl)-ethanone::CHEMBL186303

SMILES [O-][n+]1ccc(CC(=O)N2CCC(CC2)[C@@H]2c3ncc(Br)cc3C=Cc3cc(Cl)cc(Br)c23)cc1

InChI Key InChIKey=NBMZKTWABZIDLO-VWLOTQADSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50155778   

TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50155778(1-[4-((S)-3,10-Dibromo-8-chloro-11H-benzo[5,6]cycl...)
Affinity DataIC50:  0.320nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed