BDBM50156084 9-Cyclopentyl-6-(2-{4-[2-(4-methyl-piperazin-1-yl)-ethoxy]-benzyloxy}-phenylamino)-9H-purine-2-carbonitrile::CHEMBL189730

SMILES CN1CCN(CCOc2ccc(COc3ccccc3Nc3nc(nc4n(cnc34)C3CCCC3)C#N)cc2)CC1

InChI Key InChIKey=WAQLYLNMWXUBCF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156084   

TargetProcathepsin L(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156084(9-Cyclopentyl-6-(2-{4-[2-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50:  560nMAssay Description:Inhibitory concentration against recombinant human cathepsin L by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156084(9-Cyclopentyl-6-(2-{4-[2-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration against recombinant human cathepsin S by using Z-Leu-Leu-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50156084(9-Cyclopentyl-6-(2-{4-[2-(4-methyl-piperazin-1-yl)...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against recombinant human cathepsin K by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed