BDBM50157075 2-[(4R)-4-[(2S,18R)-6-{2-[(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)carbonyloxy]ethyl}-2,18-dimethyl-6,7-diazapentacyclo[11.7.0.0^{2,10}.0^{4,8}.0^{14,18}]icosa-4,7-dien-17-yl]pentanamido]acetic acid::CHEMBL182697

SMILES COc1cc2CCN(Cc2cc1OC)C(=O)OCCn1cc2C[C@@]3(C)C(CCC4C5CCC([C@H](C)CCC(=O)NCC(O)=O)[C@@]5(C)CCC34)Cc2n1

InChI Key InChIKey=ORHZKZBQICEILG-MQCWFGOZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157075   

TargetSodium/bile acid cotransporter(Homo sapiens (Human))
Xenoport

Curated by ChEMBL
LigandPNGBDBM50157075(2-[(4R)-4-[(2S,18R)-6-{2-[(6,7-dimethoxy-1,2,3,4-t...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibition of taurocholate binding to liver bile acid transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIleal sodium/bile acid cotransporter(Homo sapiens (Human))
Xenoport

Curated by ChEMBL
LigandPNGBDBM50157075(2-[(4R)-4-[(2S,18R)-6-{2-[(6,7-dimethoxy-1,2,3,4-t...)
Affinity DataIC50:  3.20E+4nMAssay Description:In vitro inhibition of taurocholate binding to human ileal bile acid transporter expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed