BDBM50158460 (3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran-3-yl)methanone::2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran::3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketone::Benzbromarone::CHEMBL388590::US9725430, Compound 1::US9856239, benzbromarone::US9962362, Compound 1::Uroleap (TN)::cid_2333

SMILES CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1

InChI Key InChIKey=WHQCHUCQKNIQEC-UHFFFAOYSA-N

Data  4 KI  51 IC50  1 Kd  5 EC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50158460   

TargetEyes absent homolog 3 [223-510](Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Affinity DataIC50:  1.10E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEyes absent homolog 3(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Affinity DataIC50:  8.30E+3nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Cincinnati Childrens Hospital Medical Center

US Patent
LigandPNGBDBM50158460((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)
Affinity DataIC50:  5.38E+4nMAssay Description:An inhibitory assay was conducted using the previously described p-nitrophenylphosphate assay (Rayapureddi, J. P. et al. Nature 426, 295-298 (2003))....More data for this Ligand-Target Pair
In DepthDetails US Patent