BDBM50158828 CHEMBL3786528

SMILES CCc1c(C)nc2c(cnn2c1OC)C#N

InChI Key InChIKey=NIROIUUITQXVHP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50158828   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158828(CHEMBL3786528)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5A (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158828(CHEMBL3786528)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant His6-tagged KDM4C (350 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using H3K9me3 (1 to 21 resi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158828(CHEMBL3786528)
Affinity DataIC50:  324nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158828(CHEMBL3786528)
Affinity DataIC50:  324nMAssay Description:Inhibition of KDM5A (unknown origin) using ART(Kme3)QTARKSTGGKAPRKQLA-NovaTagPEG-biotin/1 uM 2-OG as substrate/co-factor by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158828(CHEMBL3786528)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of recombinant full length FLAG-tagged KDM5B (unknown origin) expressed in sf9 cells using biotin-H3K4me3 (1 to 21 residues as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed