BDBM50158844 CHEMBL3785491

SMILES Oc1cc(cc2cccnc12)-c1cccc(c1)C(=O)NCCCc1ccccc1

InChI Key InChIKey=NYKBXXGHEMXSBB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50158844   

TargetLysine-specific demethylase 4B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158844(CHEMBL3785491)
Affinity DataIC50:  10nMAssay Description:Inhibition of human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using H3K4me3 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158844(CHEMBL3785491)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KDM4C (1 to 350 residues) (unknown origin) expressed in Escherichia coli using H3K4me3 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4B(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158844(CHEMBL3785491)
Affinity DataIC50:  10nMAssay Description:Inhibition of human KDM4B (1 to 500 residues) measured by antibody-based fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158844(CHEMBL3785491)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of KDM4A (1 to 350 residues) (unknown origin) expressed in Escherichia coli using H3K4me3 as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50158844(CHEMBL3785491)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of KDM5A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed