BDBM50159202 N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-3-trifluoromethyl-benzenesulfonamide::N-[3-((S)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-3-trifluoromethyl-benzenesulfonamide

SMILES CN1CCCC1Cc1c[nH]c2ccc(NS(=O)(=O)c3cccc(c3)C(F)(F)F)cc12

InChI Key InChIKey=ZVQLQRWNPNZTMX-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50159202   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159202(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataKi:  1nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159202(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]LSD binding to human 5-hydroxytryptamine 6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159202(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataEC50:  3.20nMAssay Description:Effective agonist concentration in cAMP release assay in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50159202(N-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...)
Affinity DataIC50:  14.1nMAssay Description:Inhibition of 5-HT stimulated cAMP production in HeLa cells expressing human 5-hydroxytryptamine 6 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed