BDBM50159940 CHEMBL3785228::US10093640, Example 255::US10844032, Example 255

SMILES Cc1cc(OCCCc2c([nH]c3cc(Cl)ccc23)C(=O)NS(=O)(=O)CCNC(=O)c2cccc(c2)C(F)(F)F)cc(C)c1Cl

InChI Key InChIKey=DXESQVROCCECGJ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50159940   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 [172-327](Homo sapiens (Human))
Vanderbilt University

US Patent
LigandPNGBDBM50159940(CHEMBL3785228 | US10093640, Example 255 | US108440...)
Affinity DataKi: <100nMAssay Description:The assay was run using a fluorescein isothiocyanate-labeled BH3 peptide derived from Bak (FITC-AHx-GQVGRQLAIIGDDINR-NH2) that was purchased from Gen...More data for this Ligand-Target Pair
In DepthDetails US Patent