BDBM50161047 5-Methyl-3-phenyl-isoxazole-4-carboxylic acid (4-diethylamino-phenyl)-amide::CHEMBL361366

SMILES CCN(CC)c1ccc(NC(=O)c2c(C)onc2-c2ccccc2)cc1

InChI Key InChIKey=UDDOZWWBHVIGDS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50161047   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50161047(5-Methyl-3-phenyl-isoxazole-4-carboxylic acid (4-d...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of binding to human growth hormone secretagogue receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomeobox protein Nkx-2.5/Transcription factor GATA-4(Mus musculus)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50161047(5-Methyl-3-phenyl-isoxazole-4-carboxylic acid (4-d...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50161047(5-Methyl-3-phenyl-isoxazole-4-carboxylic acid (4-d...)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of ghrelin-induced increase of intracellular [Ca2+] in CHO¿K cell FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed