BDBM50162073 (S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)ethyl 2-amino-3-methylbutanoate::(S)-2-Amino-3-methyl-butyric acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester::CHEMBL1349::VALACYCLOVIR

SMILES CC(C)[C@H](N)C(=O)OCCOCn1cnc2c1nc(N)[nH]c2=O

InChI Key InChIKey=HDOVUKNUBWVHOX-QMMMGPOBSA-N

Data  9 KI  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50162073   

TargetSolute carrier family 15 member 2(Rattus norvegicus)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50162073((S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)et...)
Affinity DataKi:  2.20E+5nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSolute carrier family 15 member 2(Rattus norvegicus)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50162073((S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)et...)
Affinity DataKi:  2.20E+5nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSolute carrier family 15 member 1(Rattus norvegicus)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50162073((S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)et...)
Affinity DataKi:  2.50E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSolute carrier family 15 member 1(Rattus norvegicus)
Kyoto University Hospital

Curated by ChEMBL
LigandPNGBDBM50162073((S)-2-((2-amino-6-oxo-3H-purin-9(6H)-yl)methoxy)et...)
Affinity DataKi:  2.70E+6nMAssay Description:TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed