BDBM50163838 (1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cyclohexyl-1-methyl-ethyl ester::CHEMBL183660::TCMDC-138496

SMILES C[C@@H](CC1CCCCC1)OC(=O)N[C@H]1CCN(C1)C#N

InChI Key InChIKey=GLZGNFOBDIGKFZ-JSGCOSHPSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50163838   

TargetPro-cathepsin H(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibitory concentration against human cathepsin H using 50 uM L-Arg-beta-naphthalamideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...)
Affinity DataIC50:  680nMAssay Description:Inhibitory concentration against human cathepsin B using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...)
Affinity DataIC50:  81nMAssay Description:Inhibitory concentration against human cathepsin L using 5 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50163838((1-Cyano-pyrrolidin-3-yl)-carbamic acid (S)-2-cycl...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against human cathepsin K using 10 uM Cbz-Phe-Arg-AMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed