BDBM50164691 CHEMBL372464::N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(4-methoxy-phenyl)-5-trifluoromethyl-pyrimidine-2,4-diamine

SMILES COc1ccc(Nc2nc(Nc3ccc4nc[nH]c4c3)ncc2C(F)(F)F)cc1

InChI Key InChIKey=VMXUAXSUFHWVMR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50164691   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(CHEMBL372464 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  57nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(CHEMBL372464 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against Extracellular signal-regulated kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(CHEMBL372464 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  57nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50164691(CHEMBL372464 | N*2*-(3H-Benzoimidazol-5-yl)-N*4*-(...)
Affinity DataIC50:  8nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed