BDBM50164871 1-(3,5-Diphenyl-4,5-dihydro-pyrazol-1-yl)-ethanone::1-(3,5-diphenyl-4,5-dihydro-1H-pyrazol-1-yl)ethanone::4,5-Dihydro-(1H)-pyrazole derivative, 1a::CHEMBL193585

SMILES CC(=O)N1N=C(CC1c1ccccc1)c1ccccc1

InChI Key InChIKey=BSTJKGVHQLTINE-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50164871   

TargetCathepsin H(Capra hircus (Goat))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50164871(1-(3,5-Diphenyl-4,5-dihydro-pyrazol-1-yl)-ethanone...)
Affinity DataKi:  1.75E+4nMAssay Description:Non-competitive inhibition of goat liver cathepsin H using Leu-betaNA substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Capra hircus (Goat))
Kurukshetra University

Curated by ChEMBL
LigandPNGBDBM50164871(1-(3,5-Diphenyl-4,5-dihydro-pyrazol-1-yl)-ethanone...)
Affinity DataKi:  1.77E+4nMAssay Description:Non-competitive inhibition of goat liver cathepsin B using BANA substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Indo-Soviet Friendship College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50164871(1-(3,5-Diphenyl-4,5-dihydro-pyrazol-1-yl)-ethanone...)
Affinity DataIC50:  6.14E+4nMAssay Description:Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
UniversitÀ

LigandPNGBDBM50164871(1-(3,5-Diphenyl-4,5-dihydro-pyrazol-1-yl)-ethanone...)
Affinity DataIC50:  9nMAssay Description:Monoamine oxidase inhibitory activity of derivatives of 4, dihydro-(1H)-pyrazole.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50164871(1-(3,5-Diphenyl-4,5-dihydro-pyrazol-1-yl)-ethanone...)
Affinity DataIC50: >5.00E+4nMAssay Description:In vitro inhibitory concentration towards kinesin spindle protein activity of ATP hydrolysis in the presence of microtubules measured by ATPase assay...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
UniversitÀ

LigandPNGBDBM50164871(1-(3,5-Diphenyl-4,5-dihydro-pyrazol-1-yl)-ethanone...)
Affinity DataIC50:  4.10E+4nMAssay Description:Monoamine oxidase inhibitory activity of derivatives of 4, dihydro-(1H)-pyrazole.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed