BDBM50165447 2-Amino-5-(3,5-bis-trifluoromethyl-phenylsulfanyl)-6-methyl-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL195874

SMILES Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=MEXFJYCVDSFQPN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165447   

TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165447(2-Amino-5-(3,5-bis-trifluoromethyl-phenylsulfanyl)...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory concentration against human dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165447(2-Amino-5-(3,5-bis-trifluoromethyl-phenylsulfanyl)...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibitory concentration against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50165447(2-Amino-5-(3,5-bis-trifluoromethyl-phenylsulfanyl)...)
Affinity DataIC50: >2.10E+4nMAssay Description:Inhibitory concentration against human thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed