BDBM50165468 CHEMBL3799263

SMILES CCCn1cc(cn1)-c1cnc2nnc(n2n1)C(F)(F)c1ccc2ncccc2c1

InChI Key InChIKey=TUHCLUVEAHXQCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50165468   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165468(CHEMBL3799263)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165468(CHEMBL3799263)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of c-Met in human EBC-1 cells assessed as reduction in cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed