BDBM50165469 CHEMBL3797911

SMILES COc1ccc2c(OCc3nnc4ncc(nn34)-c3ccccc3)ccnc2c1

InChI Key InChIKey=DYQKJQPOOQEANS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50165469   

TargetNucleoprotein TPR(Mus musculus)
Chinese Academy Of Sciences (Cas)

Curated by ChEMBL
LigandPNGBDBM50165469(CHEMBL3797911)
Affinity DataIC50:  80nMAssay Description:Inhibition of TPR-MET in mouse NIH/3T3 cells assessed as inhibition of cell proliferation after 72 hrs by SRB or MTT assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50165469(CHEMBL3797911)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of c-Met (unknown origin) using poly(Glu-Tyr) at 4:1 ratio as substrate in presence of ATP incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50165469(CHEMBL3797911)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of recombinant c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate incubated for 60 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed