BDBM50165936 Ac-dR[CEHdFRWC]-NH2::CHEMBL267900

SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](Cc2cnc[nH]2)NC(=O)[C@H](CCC(O)=O)NC1=O)C(N)=O

InChI Key InChIKey=UNXFCHHFXJFRRB-ABRXVHCYSA-N

Data  5 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50165936   

TargetMelanocortin receptor 4(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataKi:  0.390nMAssay Description:Binding affinity for rat melanocortin-4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataKi:  0.550nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataKi:  17nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataKi:  57nMAssay Description:Inhibition of [125I]-NDP-alpha-MSH binding to melanocortin-3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataKi: >500nMAssay Description:Inhibition of [125I]NDP-alpha-MSH binding to melanocortin-5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataEC50:  0.280nMAssay Description:Agonist activity at human Melanocortin-4 receptor as peptide required for 50% maximal cAMP release (n > or =2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50165936(Ac-dR[CEHdFRWC]-NH2 | CHEMBL267900)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human Melanocortin-3 receptor as peptide required for 50% maximal cAMP releaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed