BDBM50166950 CHEMBL3799428
SMILES CCC(=O)N1CCN(CC1)c1ccc(Nc2ncc(SC)c(Oc3cccc(NC(=O)C=C)c3)n2)c(OC(F)F)c1
InChI Key InChIKey=YDWRFDRHSNTINI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50166950
Affinity DataIC50: 3.70nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Inhibition of wild-type EGFR (unknown origin) expressed in baculovirus expression system after 1 hr by ELISAMore data for this Ligand-Target Pair