BDBM50167033 (1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid::CHEMBL192977

SMILES C[C@@H]1C[C@H]2[C@@H]([C@H]2[C@]1(N)C(O)=O)C(O)=O

InChI Key InChIKey=XMDHIHAVEVYYTH-QNDZYWSYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50167033   

TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  146nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataKi:  983nMAssay Description:Displacement of [3H]-341495 binding to membranes expressing recombinant human Metabotropic glutamate receptor 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataIC50:  9.83E+3nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50167033((1S,2S,3R,5R,6S)-2-Amino-3-methyl-bicyclo[3.1.0]he...)
Affinity DataIC50:  1.75E+3nMAssay Description:Evaluation of the functional effect on cAMP responses in RGT cells expressing human mGlu2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed