BDBM50168825 1-(3-Chloro-4-fluoro-phenyl)-3-[2-(3'-cyano-biphenyl-4-yl)-4-dimethylamino-butyl]-urea::1-(3-chloro-4-fluorophenyl)-3-(2-(3'-cyanobiphenyl-4-yl)-4-(dimethylamino)butyl)urea::CHEMBL361215

SMILES CN(C)CCC(CNC(=O)Nc1ccc(F)c(Cl)c1)c1ccc(cc1)-c1cccc(c1)C#N

InChI Key InChIKey=NQSBVOSOIXBYRP-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50168825   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50168825(1-(3-Chloro-4-fluoro-phenyl)-3-[2-(3'-cyano-biphen...)
Affinity DataKi:  0.980nMAssay Description:Inhibitiory constant towards Human melanin-concentrating hormone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50168825(1-(3-Chloro-4-fluoro-phenyl)-3-[2-(3'-cyano-biphen...)
Affinity DataKi:  0.980nMAssay Description:Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Pharmacopeia Drug Discovery

Curated by ChEMBL
LigandPNGBDBM50168825(1-(3-Chloro-4-fluoro-phenyl)-3-[2-(3'-cyano-biphen...)
Affinity DataIC50:  0.980nMAssay Description:Antagonist activity at MCHR1 (unknown origin) expressed in CHO cells co-expressing aequorin incubated for 10 mins by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed