BDBM50169060 CHEMBL3804939
SMILES COc1ccc(cc1C)C(=O)C1CCN(CC1)C(=O)CCCc1nc2c(C)scc2c(=O)[nH]1
InChI Key InChIKey=PPFZSMPPXPFDAK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50169060
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 0.190nMAssay Description:Inhibition of GST-tagged TNKS2 (873 to 1166 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1/tankyrase-2(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataEC50: 1.30nMAssay Description:Inhibition of tankyrase in human DLD1 cells assessed as increase in axin2 level after 24 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GST-tagged TNKS1 (1023 to 1327 residues) (unknown origin) autoparsylation using biotinylated NAD incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Therachem Research Medilab (India)
Curated by ChEMBL
Therachem Research Medilab (India)
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant His-tagged PARP1 autoparsylation expressed in sf21 cells using NAD and biotinylated NAD incubated for 150 mins by HTR...More data for this Ligand-Target Pair