BDBM50169389 1-[4-(3'-Cyano-biphenyl-4-yl)-1-cyclopentyl-piperidin-4-ylmethyl]-3-(3,5-dichloro-phenyl)-urea::CHEMBL361392
SMILES Clc1cc(Cl)cc(NC(=O)NCC2(CCN(CC2)C2CCCC2)c2ccc(cc2)-c2cccc(c2)C#N)c1
InChI Key InChIKey=YWTHSNUPDVPAPM-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50169389
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataKi: 0.630nMAssay Description:Ability to displace [125-I]-MCH()0.5 nM from human MCH1R(2.5 uM) expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Pharmacopeia Drug Discovery
Curated by ChEMBL
Pharmacopeia Drug Discovery
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Binding affinity at human MCHR1 assessed as inhibition of MCH-mediated calcium ion influx by FLIPR assayMore data for this Ligand-Target Pair