BDBM50170210 CHEMBL367148::[4-(4-Trifluoromethoxy-phenyl)-thiophene-2-carbonyl]-carbamic acid 4-methyl-benzyl ester

SMILES Cc1ccc(COC(=O)NC(=O)c2cc(cs2)-c2ccc(OC(F)(F)F)cc2)cc1

InChI Key InChIKey=FMBCNTQGGGDHCQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50170210   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50170210(CHEMBL367148 | [4-(4-Trifluoromethoxy-phenyl)-thio...)
Affinity DataIC50:  400nMAssay Description:Inhibition of Matrix metalloprotease-12 in presence of 5 nM acetohydroximateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed