BDBM50170480 6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyridine-2-carboxylic acid (4-hydroxycarbamoylmethyl-thiazol-2-yl)-amide::CHEMBL366118

SMILES CCc1cc(C(C)=O)c(O)cc1OCc1cccc(n1)C(=O)Nc1nc(CC(=O)NO)cs1

InChI Key InChIKey=ZABQHWUKKILDGH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50170480   

LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  87nMAssay Description:Inhibitory concentration against Phosphodiesterase type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitory concentration against Phosphodiesterase type 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50170480(6-(4-Acetyl-2-ethyl-5-hydroxy-phenoxymethyl)-pyrid...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against Phosphodiesterase type 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed