BDBM50173532 1-[5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-fluoro-tetrahydro-furan-2-yl]-1H-pyrimidine-2,4-dione::CHEMBL370908::dUTPase inhibitor, 7
SMILES CC(C)(C)[Si](OCC1OC(CC1F)n1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1
InChI Key InChIKey=XHPAXDNHQFGCEQ-UHFFFAOYSA-N
Data 6 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50173532
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataKi: 8.90E+4nMAssay Description:Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
Cardiff University
Curated by ChEMBL
Cardiff University
Curated by ChEMBL
Affinity DataKi: 8.94E+4nM ΔG°: -5.52kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 8.07E+5nM ΔG°: -4.22kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 8.08E+5nMAssay Description:Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+9nM ΔG°: 0kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair