BDBM50173537 CHEMBL197746::Sulfamic acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2,5-dihydro-furan-2-ylmethyl ester

SMILES NS(=O)(=O)OCC1OC(C=C1)n1ccc(=O)[nH]c1=O

InChI Key InChIKey=JNTYPENMQJEONP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173537   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50173537(CHEMBL197746 | Sulfamic acid 5-(2,4-dioxo-3,4-dihy...)
Affinity DataKi:  2.54E+5nMAssay Description:Inhibitory constant against Plasmodium falciparum deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50173537(CHEMBL197746 | Sulfamic acid 5-(2,4-dioxo-3,4-dihy...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against human deoxyuridine 5'-triphosphate nucleotidohydrolase expressed in Escherichia coli BL21 (DE3) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPutative deoxyuridine triphosphatase(Leishmania major)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50173537(CHEMBL197746 | Sulfamic acid 5-(2,4-dioxo-3,4-dihy...)
Affinity DataKi: >1.00E+6nMAssay Description:Inhibitory constant against Leishmania major deoxyuridine 5'-triphosphate nucleotidohydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed