BDBM50173548 CHEMBL373232::Phosphoric acid 5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester diphenyl ester::dUTPase inhibitor, 1

SMILES OC1CC(OC1COP(=O)(Oc1ccccc1)Oc1ccccc1)n1ccc(=O)[nH]c1=O

InChI Key InChIKey=IHWNCZRHSNSIGL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50173548   

TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra

LigandPNGBDBM50173548(CHEMBL373232 | Phosphoric acid 5-(2,4-dioxo-3,4-di...)
Affinity DataKi:  1.35E+5nM ΔG°:  -5.28kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra

LigandPNGBDBM50173548(CHEMBL373232 | Phosphoric acid 5-(2,4-dioxo-3,4-di...)
Affinity DataKi:  2.38E+5nM ΔG°:  -4.94kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP deaminase(Campylobacter jejuni)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra

LigandPNGBDBM50173548(CHEMBL373232 | Phosphoric acid 5-(2,4-dioxo-3,4-di...)
Affinity DataKi:  1.00E+6nM ΔG°:  -4.09kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed