BDBM50173566 1-(4-Hydroxy-5-triisopropylsilanyloxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione::CHEMBL199038::dUTPase inhibitor, 10
SMILES CC(C)[Si](OCC1OC(CC1O)n1ccc(=O)[nH]c1=O)(C(C)C)C(C)C
InChI Key InChIKey=ZKTWJRLCMJWTCV-UHFFFAOYSA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50173566
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase(Plasmodium falciparum)
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 2.27E+5nM ΔG°: -4.97kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
TargetDeoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial(Homo sapiens (Human))
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Instituto De Parastiologia Y Biomedicina "Lopez-Neyra
Affinity DataKi: 1.00E+6nM ΔG°: -4.09kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+9nM ΔG°: 0kcal/molepH: 8.0 T: 2°CAssay Description:Nucleotide hydrolysis was monitored by mixing enzyme and substrate with a rapid kinetic accessory (Hi-Tech Scientific) attached to a spectrophotomete...More data for this Ligand-Target Pair