BDBM50173765 BPH-308::CHEMBL196749::[2-(2',4'-Difluoro-biphenyl-3-yl)-1-hydroxy-1-phosphono-ethyl]-phosphonic acid

SMILES OC(Cc1cccc(c1)-c1ccc(F)cc1F)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=SQJZGUCJSOQOMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50173765   

TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50173765(BPH-308 | CHEMBL196749 | [2-(2',4'-Difluoro-biphen...)
Affinity DataIC50:  1.38E+5nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis H37Rv)
University of California San Diego

LigandPNGBDBM50173765(BPH-308 | CHEMBL196749 | [2-(2',4'-Difluoro-biphen...)
Affinity DataIC50:  4.30E+3nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed