BDBM50176050 8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione::8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-1,3-diethyl-7-methyl-3,7-dihydro-purine-2,6-dione::8-[2-(3,4-dimethoxy-phenyl)-vinyl]-1,3-diethyl-7-methyl-3,9-dihydro-purine-2,6-dione::CHEMBL431770::US11806350, Compound Istradefylline::istradefylline
SMILES CCn1c2nc(\C=C\c3ccc(OC)c(OC)c3)n(C)c2c(=O)n(CC)c1=O
InChI Key InChIKey=IQVRBWUUXZMOPW-PKNBQFBNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50176050
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat brain striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]CGS21680 from adenosine A2A receptor in rat brain after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [3H]CGS21680 from human adenosine A2A receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 36nMAssay Description:Displacement of [3H]MSX2 from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 91nMAssay Description:Displacement of [3H]MSX2 from human recombinant adenosine A2A receptor expressed in CHO cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor in rat brain after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 230nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membranes after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 841nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 90 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 841nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.83E+3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataKi: 4.47E+3nMAssay Description:Displacement of [3H]PSB-11 from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by liquid scintillation counting analysi...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human adenosine A2B receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PSB-603 from human recombinant adenosine A2B receptor expressed in CHO cells after 75 mins by liquid scintillation counting analy...More data for this Ligand-Target Pair