BDBM50176126 (Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]-2-hydroxy-4-oxo-but-2-enoic acid::CHEMBL363170

SMILES OC(=O)C(=O)CC(=O)c1cn(Cc2ccc(F)cc2)c2ccc(Cl)cc12

InChI Key InChIKey=QCQMAUKGBNJJIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50176126   

TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176126((Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]...)
Affinity DataIC50:  10nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176126((Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]...)
Affinity DataIC50:  200nMAssay Description:In vitro concentration required to inhibit the overall HIV-1 integrase strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Università

Curated by ChEMBL
LigandPNGBDBM50176126((Z)-4-[5-Chloro-1-(4-fluoro-benzyl)-1H-indol-3-yl]...)
Affinity DataIC50:  1.59E+3nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase 3' strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed