BDBM50176341 4-(4-chloro-3-hydroxyphenyl)-N-(3-(dimethylamino)propyl)-5-(pyridin-4-yl)-1H-imidazole-2-carboxamide::CHEMBL426476

SMILES CN(C)CCCNC(=O)c1nc(c([nH]1)-c1ccc(Cl)c(O)c1)-c1ccncc1

InChI Key InChIKey=JKGOUELCADFHSY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50176341   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50176341(4-(4-chloro-3-hydroxyphenyl)-N-(3-(dimethylamino)p...)
Affinity DataIC50:  40nMAssay Description:Inhibition bRaf kinase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50176341(4-(4-chloro-3-hydroxyphenyl)-N-(3-(dimethylamino)p...)
Affinity DataKd:  24nMAssay Description:Binding affinity at bRaf kinase in fluorescent ligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed