BDBM50177074 9-(Ethyl-methyl-amino)-3-(4-ethyl-phenyl)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::9-(N,N-ethylmethylamino)-3-(4'-ethylphenyl)-3H-5-thia-1,3,6-triazafluoren-4-one::CHEMBL223543

SMILES CCN(C)c1ccnc2sc3c(ncn(-c4ccc(CC)cc4)c3=O)c12

InChI Key InChIKey=IPMMMSQQYJZTAG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50177074   

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177074(9-(Ethyl-methyl-amino)-3-(4-ethyl-phenyl)-3H-pyrid...)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human mGluR1 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(RAT)
Biocampus

Curated by ChEMBL
LigandPNGBDBM50177074(9-(Ethyl-methyl-amino)-3-(4-ethyl-phenyl)-3H-pyrid...)
Affinity DataIC50:  37nMAssay Description:Inhibition of rat mGluR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50177074(9-(Ethyl-methyl-amino)-3-(4-ethyl-phenyl)-3H-pyrid...)
Affinity DataIC50:  2.57E+3nMAssay Description:Antagonist activity at human mGluR5 expressed in 1321N1 cells assessed as effect on L-glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed