BDBM50177111 3-alpha-(4-methylphenyl)-2-beta-(3,4-dimethoxyphenyl)tropane::CHEMBL388825

SMILES COc1ccc(cc1OC)[C@@H]1C2CCC(C[C@H]1c1ccc(C)cc1)N2C

InChI Key InChIKey=UBUINJQFQXKDNL-XKXWHVAQSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50177111   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177111(3-alpha-(4-methylphenyl)-2-beta-(3,4-dimethoxyphen...)
Affinity DataKi:  1.47E+3nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177111(3-alpha-(4-methylphenyl)-2-beta-(3,4-dimethoxyphen...)
Affinity DataKi:  4.60E+4nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177111(3-alpha-(4-methylphenyl)-2-beta-(3,4-dimethoxyphen...)
Affinity DataIC50:  1.62E+4nMAssay Description:Displacement of [3H]paroxetine from 5HTTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177111(3-alpha-(4-methylphenyl)-2-beta-(3,4-dimethoxyphen...)
Affinity DataIC50:  980nMAssay Description:Displacement of [3H]WIN-35428 from DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50177111(3-alpha-(4-methylphenyl)-2-beta-(3,4-dimethoxyphen...)
Affinity DataIC50:  7.80E+4nMAssay Description:Displacement of [3H]nisoxetine from NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed