BDBM50177539 1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-yl)propoxy)benzyl)piperidin-2-one::CHEMBL204705

SMILES O=C1CCCCN1Cc1ccc(OCCCN2CCC(Cc3cnc[nH]3)CC2)cc1

InChI Key InChIKey=AAKBFDPOXZBIAO-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50177539   

TargetHistamine H3 receptor(GUINEA PIG)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177539(1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from guinea pig histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50177539(1-(4-(3-(4-((1H-imidazol-4-yl)methyl)piperidin-1-y...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of CYP2D6 by supersome assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed