BDBM50179207 3-fluoro-N-(6,7-dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamine::CHEMBL120077::JNJ-10198409
SMILES COc1cc2Cc3c(Nc4cccc(F)c4)[nH]nc3-c2cc1OC
InChI Key InChIKey=ZDNURMVOKAERHZ-UHFFFAOYSA-N
Data 34 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50179207
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cdk1Checked by AuthorMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of PDGFRbetaChecked by AuthorMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER2Checked by AuthorMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of PDGFRalphaChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of cAblChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of LckChecked by AuthorMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 185nMAssay Description:Inhibition of c-SrcChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 378nMAssay Description:Inhibition of FynChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cdk2Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Cdk4Checked by AuthorMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University Of Oxford
Curated by ChEMBL
University Of Oxford
Curated by ChEMBL
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of bFGFR1Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human EGFR at 10000 nMChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Cdk7Checked by AuthorMore data for this Ligand-Target Pair