BDBM50179654 1-(3-chlorophenyl)-3-(1-ethyl-4-oxoimidazolidin-2-ylidene)urea::CHEMBL202794

SMILES CCn1cc(O)nc1NC(=O)Nc1cccc(Cl)c1

InChI Key InChIKey=XTMHABCKCABPRE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50179654   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179654(1-(3-chlorophenyl)-3-(1-ethyl-4-oxoimidazolidin-2-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of glutamate-induced calcium influx in human mGluR5d by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50179654(1-(3-chlorophenyl)-3-(1-ethyl-4-oxoimidazolidin-2-...)
Affinity DataIC50:  180nMAssay Description:Displacement of [3H]MPEP from mGluR5d in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed