BDBM50180182 CHEMBL369919::bis-((-)-N-[(S)-tetrahydrofurfuryl]morphinan-3-yl) sebacoylate

SMILES O=C(CCCCCCCCC(=O)Oc1ccc2C[C@@H]3C4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1)Oc1ccc2C[C@@H]3C4CCCC[C@]4(CCN3C[C@@H]3CCCO3)c2c1

InChI Key InChIKey=XPVQMCQVPCFYJK-LHQHLCNUSA-N

Data  3 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50180182   

TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataKi:  0.670nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataKi:  8.30nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataEC50:  12nMAssay Description:Activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataEC50:  8.80nMAssay Description:Displacement of [3H]U69593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50180182(CHEMBL369919 | bis-((-)-N-[(S)-tetrahydrofurfuryl]...)
Affinity DataIC50:  360nMAssay Description:Activity at human mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed