BDBM50180920 7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2,3-g]azecine::CHEMBL382850

SMILES CCN1CCc2c(Cc3ccccc3CC1)[nH]c1ccccc21

InChI Key InChIKey=HNSLMUBRFVOOOR-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50180920   

TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  14.7nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  16.4nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  22.3nMAssay Description:Inhibition of binding to human D5 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  82.6nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  170nMAssay Description:Inhibition of binding to human D1 receptor expressed in HEK 293 cells by functional calcium assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  253nMAssay Description:Inhibition of binding to human D2L receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50180920(7-ethyl-6,7,8,9,14,15-hexahydro-5H-benz[d]indolo[2...)
Affinity DataKi:  379nMAssay Description:Inhibition of binding to human D4 receptor expressed in HEK 293 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed