BDBM50181073 2-(3-chloro-benzyloxy)-6-methyl-isonicotinonitrile::CHEMBL207703

SMILES Cc1cc(cc(OCc2cccc(Cl)c2)n1)C#N

InChI Key InChIKey=XDGUYOFWWFFLND-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50181073   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50181073(2-(3-chloro-benzyloxy)-6-methyl-isonicotinonitrile...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]MPEP from recombinant human mGlu5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50181073(2-(3-chloro-benzyloxy)-6-methyl-isonicotinonitrile...)
Affinity DataIC50:  9nMAssay Description:Inhibition of mGlu5 receptor by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed